Structural and Functional Brain Abnormalities in Schizophrenia

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Structural and Functional Brain Abnormalities in Schizophrenia.

Schizophrenia is associated with changes in the structure and functioning of a number of key brain systems, including prefrontal and medial temporal lobe regions involved in working memory and declarative memory, respectively. Imaging techniques provide an unparalleled window into these changes, allowing repeated assessments across pre- and post-onset stages of the disorder and in relation to c...

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Whole brain resting state functional connectivity abnormalities in schizophrenia.

BACKGROUND Schizophrenia has been associated with disturbances in brain connectivity; however the exact nature of these disturbances is not fully understood. Measuring temporal correlations between the functional MRI time courses of spatially disparate brain regions obtained during rest has recently emerged as a popular paradigm for estimating brain connectivity. Previous resting state studies ...

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ژورنال

عنوان ژورنال: Current Directions in Psychological Science

سال: 2010

ISSN: 0963-7214,1467-8721

DOI: 10.1177/0963721410377601